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Patent Granted Disclosed are: a lymphangiogenesis inhibitor comprising vasohibin; a lymphangiogenesis inhibitor comprising a vector carrying a polynucleotide encoding vasohibin; a pharmaceutical composition for the treatment of a disease for which a lymphangiogenesis inhibitory effect is required, which comprises the inhibitor; use of vasohibin for the production of a pharmaceutical composition for the treatment of a disease for which a lymphangiogenesis inhibitory effect is required.