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Patent Pending Esophageal cancer (or oesophageal cancer) is cancer arising from the esophagus—the foodpipe that runs between the throat and the stomach.[1] Symptoms often include trouble swallowing and weight loss. Other symptoms may include pain with swallowing, a hoarse voice, enlarged lymph nodes (glands) around the clavicle (collarbone), a dry cough, and possibly coughing up or vomiting blood.