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Patent Pending The Epstein–Barr virus nuclear antigen 3 (EBNA-3) is a family of viral proteins associated with the Epstein–Barr virus.[citation needed] EBNA-3A[clarification needed] EBNA-3B[clarification needed] EBNA-3C[clarification needed] These genes also bind the host RBP-Jκ protein.[clarification needed][citation needed] EBNA-3C can recruit[clarification needed] a ubiquitin ligase and has been shown to target cell-cycle regulators such as retinoblastoma protein (pRb).