GPCR ligands

Patent Pending G protein-coupled receptors are found only in eukaryotes, including yeast, choanoflagellates,[2] and animals. The ligands that bind and activate these receptors include light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters, and vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases, and are also the target of approximately 40% of all modern medicinal drugs.