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Patent Pending High frequency oscillatory ventilation was first described in 1972 and is used in neonates and adult patient populations to reduce lung injury, or to prevent further lung injury. HFOV is characterized by high respiratory rates between 3.5 to 15 hertz (210 - 900 breaths per minute) and having both inhalation and exhalation maintained by active pressures. The rates used vary widely depending upon patient size, age, and disease process. In HFOV the pressure oscillates around the constant distending pressure (equivalent to mean airway pressure [MAP]) which in effect is the same as positive end-expiratory pressure (PEEP). Thus gas is pushed into the lung during inspiration, and then pulled out during expiration. HFOV generates very low tidal volumes that are generally less than the dead space of the lung. Tidal volume is dependent on endotracheal tube size, power and frequency.