B cell apoptosis

Patent Pending When the B cell fails in any step of the maturation process, it will die by a mechanism called apoptosis, here called clonal deletion.[6] B cells are continuously produced in the bone marrow. When the B cell receptor, on the surface of the cell, matches the detected antigens present in the body, the B cell proliferates and secretes a free form of those receptors (antibodies) with identical binding sites as the ones on the original cell surface.