Glioblastoma multiforme

Patent Pending Glioblastoma multiforme (GBM), WHO classification name "glioblastoma", also known as Grade IV Astrocytoma,[1] is the most common and most aggressive malignant primary brain tumor in humans, involving glial cells and accounting for 52% of all functional tissue brain tumor cases and 20% of all intracranial tumors. GBM is rare, with incidence of 2–3 cases per 100,000[clarification needed] in Europe and North America. It presents two variants: giant cell glioblastoma and gliosarcoma.