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Patent Pending Human embryonic stem cells may be grown in cell culture and stimulated to form insulin-producing cells that can be transplanted into the patient. However, clinical success is highly dependent on the development of the following procedures:[7] Transplanted cells should proliferate Transplanted cells should differentiate in a site-specific manner Transplanted cells should survive in the recipient (prevention of transplant rejection) Transplanted cells should integrate within the targeted tissue Transplanted cells should integrate into the host circuitry and restore function