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Patent Pending A radionuclide or radioactive nuclide, also referred to as a radioisotope or radioactive isotope, is an atom with an unstable nucleus, characterized by excess energy available to be imparted either to a newly created radiation particle within the nucleus or via internal conversion. During this process, the radionuclide is said to undergo radioactive decay, resulting in the emission of gamma ray(s) and/or subatomic particles such as alpha or beta particles.[1] These emissions constitute ionizing radiation. Radionuclides occur naturally, or can be produced artificially.