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Patent Pending Esophageal cancer (or oesophageal cancer) is cancer arising from the foodpipe known as the esophagus that runs between the throat and the stomach.[1] Symptoms often include difficulty in swallowing and weight loss. Other symptoms may include pain when swallowing, a hoarse voice, enlarged lymph nodes (glands) around the collarbone, a dry cough, and possibly coughing up or vomiting blood.