Activins/inhibins

Patent Granted Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Identified in 1986,[1][2] activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis,[3] metabolism, homeostasis, immune response, wound repair,[4] and endocrine function. Conversely inhibin downregulates FSH synthesis and inhibits FSH secretion.