Levopimaradiene synthase

Patent Granted Levopimaradiene synthase (EC 4.2.3.32, PtTPS-LAS, LPS, copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]) is an enzyme with system name (+)-copalyl-diphosphate diphosphate-lyase (abieta-8(14),12-diene-forming).[1][2] This enzyme catalyses the following chemical reaction (+)-copalyl diphosphate \rightleftharpoons abieta-8(14),12-diene + diphosphate In Ginkgo, the enzyme catalyses the initial cyclization step in the biosynthesis of ginkgolides.