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Patent Pending CD180 antigen is a protein that in humans is encoded by the CD180 gene.[1][2][3] CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. It is also known by the archaic terms Bgp-95 and RP105, for the founding designations following discovery in humans (1988) and mice (1994), respectively.