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Patent Pending An enkephalin is a pentapeptide involved in regulating nociception in the body. The enkephalins are termed endogenous ligands, as they are internally derived and bind to the body's opioid receptors. Discovered in 1975, two forms of enkephalin were revealed, one containing leucine ("leu"), and the other containing methionine ("met"). Both are products of the proenkephalin gene.
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