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Patent Granted Stearoyl-CoA desaturase[pronunciation?] (delta-9-desaturase) is a protein that in humans is encoded by the SCD gene.[1] Stearoyl-CoA desaturase-1 is a key enzyme in fatty acid metabolism. It is responsible for forming a double bond in Stearoyl-CoA. This is how the monounsaturated fatty acid oleic acid is produced from the saturated fatty acid stearic acid.