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Patent Pending Cocaine esterase (EC 3.1.1.84, CocE, hCE2, hCE-2, human carboxylesterase 2) is an enzyme with system name cocaine benzoylhydrolase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction cocaine + H2O \rightleftharpoons ecgonine methyl ester + benzoate Rhodococcus sp. strain MB1 and Pseudomonas maltophilia strain MB11L can utilize cocaine as sole source of carbon and energy.