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Patent Granted Cocaine increases alertness, feelings of well-being and euphoria, energy and motor activity, feelings of competence and sexuality. Common side effects include anxiety, increased temperature, paranoia, restlessness, and tooth grinding. With prolonged use, often accompanied by lack of sleep, the drug can cause itching, tachycardia, hallucinations, and paranoid delusions. Possible lethal side effects include rapid heartbeat, tremors, convulsions, markedly increased core temperature, heart attack, stroke and heart failure.