SEL-10 protein

Patent Pending F-box/WD repeat-containing protein 7 is a protein that in humans is encoded by the FBXW7 gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.