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Cross-linked hemoglobins

Patent Pending The molecule haemoglobin can be cross-linked (a covalent bond between 2 globin chains is made through chemical modification), and then polymerised using reagents such as glutaraldehyde. These modifications result in a product that has a higher P50 than that of normal haemoglobin, and an increase in the plasma half-life of up to 30 hours.

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