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Resistance to echinocandin

Patent Granted Echinocandin resistance is rare. However, cases studies have shown some resistance in C. albicans, C. glabrata, C. lusitaniae, C. tropicalis, and C. parapsilosis. Resistances include alterations in the glucan synthase (Fks1-Fks2 complex) and overexpression of efflux pumps, as well as alterations and/or overexpressions in Erg3 and Erg11.

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