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Patent Granted Serotonin 5-HT2 receptors are stimulated by monoaminergic neurotransmitters including serotonin, dopamine and norepinephrine. 5-HT2 receptor stimulation cause a buildup of intracellular inositol triphosphate and thereby an increase of cytosolic Ca2+. 5-HT2C receptor agonists are attractive drug targets that have potential use in the treatment of a number of conditions including obesity, psychiatric disorders, sexual dysfunction and urinary incontinence.
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