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Patent Granted Autoinducer-2 (AI-2), a furanosyl borate diester, is a member of a family of signaling molecules used in quorum sensing.[1] AI-2 is unique in that it is one of only a few known biomolecules incorporating boron. First identified in the marine bacterium Vibrio harveyi, AI-2 is produced and recognized by many Gram-negative and Gram-positive bacteria.