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Patent Granted Because of the Akt[1] functions above, Akt inhibitors may treat cancers such as neuroblastoma. Some Akt inhibitors have undergone clinical trials. In 2007 VQD-002 had a phase I trial.[26] In 2010 Perifosine reached phase II.[27] but it failed phase III in 2012. Miltefosine is approved for leishmaniasis and under investigation for other indications including HIV.