Chimeric immunoglobulin preparation with a specific antiviral or antibacterial effect

Patent Pending The invention relates to biotechnology and immunology. Proposed is a chimeric immunoglobulin preparation containing immunoelectrophoretically pure chimeric secretory immunoglobulin А (S-IgA), isolated from the milk serum and/or colostral serum of immunized cows, in which the bovine secretory component is substituted by a human donor component or recombinant component. The base preparation (substance) contains 6-12% chimeric S-IgA, has a pH value of 4-8 and an anticomplementary activity of at least 10 mg of protein, not activating 2 CH50, protects in >70% against infection (in the event of infection of the macroorganism in doses of 10 ID50), is not reactogenic in the case of intravenous administration, and can contain stabilizing additives in a total concentration of not more than 4%. Technical result: reduced immunogenicity and reactogenicity, and a broader range of therapeutic effectiveness.