A device and method for filtering. Technological advancement in the concentration of investigative body fluid for analysis

Patent Granted This is a patented filtration and concentration device for filtering a liquid and holding filtrate in a simple, efficient and cost effective way. The device performs reverse-filtration without requiring the use of any powered actuator for applying a pressure for filtering, while minimizing clogging of filtering medium, thus, allowing for higher filtrate volume to pass through the filtering medium. Benefits : High recovery yield, Fast and Simple to use. With this Sample Preparation Technology, bodily fluids such as urine, saliva and nasal fluid may be obtained via non-invasive methods and pre-concentrated prior to analysis. This makes it possible to perform testing for presence of biomarkers in these bodily fluids for diseases such as cancers, infectious diseases and chronic inflammation, instead of having to rely on blood samples which require invasive methods to obtain. Potential applications can be extended to the development of Lateral Flow Test Kits (Rapid Test Kits for professional or home use) for biomarkers in pre-concentrated urine, saliva or nasal fluid samples. Other possible applications for this Sample Preparation Technology can be in urinalysis, cytology, microbiology, or other life sciences, which currently utilizes centrifugation method for the pre-concentration of bodily fluids samples which is prone to errors resulting of low recovery yield.